Beyond physical health, Vitamin B12 also supports mental clarity and mood
Diluting that into an adults ~3 litres of plasma changes the arithmetic considerably, but the point stands: the vial format was designed around commercial convenience, not around any dose that the mechanistic literature identified as biologically relevant
These mechanistic insights, primarily characterized in high-income settings, also provide biological plausibility for the associations observed between low DHA status and neurodevelopmental or neurodegenerative conditions (36, 48)
While the mechanism is plausible, the evidence does not yet exist to say what it does in people, at what dose, for what problem, or in which populations, especially in women
[DOI] [PMC free article] [PubMed] [Google Scholar] 66.Brewer GJ, Powell RD
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