The biological changes that underlie cardiovascular protection, including reduced blood pressure, lower inflammatory markers, improved lipids, and decreased visceral fat, begin accumulating within the first three to six months
& Stringer, C
Drink plenty of water A glass of water a few hours after a meal puts something in your stomach, telling your brain that you are not hungry
Its a recipe for confusion
But this effect, if it exists, appears to be minimal and might be offset by the higher trough levels providing more consistent appetite control in the back half of each three-to-four day cycle
[13] Treatment was given for 104 weeks (2 years), and the occurrence of cardiovascular events, including heart attacks, strokes, and hospitalization due to unstable angina (near heart attack) were recorded and compared in the two groups of participants