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HLA-DR expression on lymphocyte subsets as a marker of disease activity in patients with systemic lupus erythematosus

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Downstream signaling involves PI3K/AKT, MAPK/ERK, and PLC- pathways, which are well-characterized drivers of synaptogenesis, dendritic spine maturation, and neuronal survival

Epigenetic Regulation NNMT activity consumes S-adenosylmethionine (SAM), the universal methyl donor required for hundreds of methylation reactions throughout the cell

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