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To be successful, manufacturers should incorporate commercial considerations into early stage clinical development decision making and be quick to revise program and portfolio strategies as new data and products emerge

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Acknowledgements J.P

[7] Therefore, it was decided to pursue development of tesofensine for the treatment of obesity

Ann Intern Med (2003) 139(11):9302.10.7326/0003-4819-139-11-200312020-00012 5 National Institutes of Health