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Background on Obesity and Its Mechanisms The prevalence of obesity is a major public health concern, because of the associated weight-related diseases that result in significant morbidity and mortality and reduced quality of life

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2 Department of Endocrinology, SANKO University Faculty of Medicine, Gaziantep, Turkey Correspondence: Nimet Ylmaz, Department of Gastroenterology, SANKO University Faculty of Medicine, Gaziantep, Turkey, Email [email protected] Background: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and dual GLP-1/GIP receptor agonists are highly effective agents for the treatment of type 2 diabetes and obesity