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JACC Cardiovasc Interv
Antibody drug conjugate: the biological missile for targeted cancer therapy
Specifically, sulfasalazine, an XCT inhibitor, appears useful in the treatment of pancreatic and small-cell lung cancer cells 69,70 , while NOV-002, a glutathione disulfide mimetic that alters the GSSG/GSH ratio and induces oxidative stress, has been favorably used in patients with HER2-negative breast cancer 71
And over time, many of the Navy Phase II.5 practices changed substantially in response to testing (the Office of Naval Research [ONR], for example, discontinued Phase II.5, while the Naval Sea Systems Command [NAVSEA] and the Naval Air Systems Command [NAVAIR] increased it but used different funding approaches)
It holds no marketing authorisation from the MHRA, so it is not a licensed medicine and may not be sold or used for human or veterinary consumption