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A deficiency of CD4+CD25+ T cells permits the development of spontaneous lupus-like disease in mice, and can be reversed by induction of mucosal tolerance to histone peptide autoantigen

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A comparison between the kinetic parameters of mutated ScGrx7 and PfGrx reveals extreme similarities and supports a general applicability of our mechanistic model

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It is important to note that, despite these convergent findings, direct mechanistic evidence demonstrating that addictive substances induce depressive phenotypes via specific epigenetic pathways remains extremely limited, with only a few studies providing clear causal links