If this describes your experience, medication-assisted weight loss may offer what previous approaches couldn't
Retatrutide works as a powerful triple-agonist, meaning it works on three key hormone receptors: The human glucagon receptor (GCGR) The glucose-dependent polypeptide receptor (GIP receptor) The glucagon-like peptide-1 receptor (GLP-1) This unique receptor profile allows retatrutide to effectively: Regulate appetite, feelings of fullness, and gastric emptying Regulate metabolism Regulate blood sugar levels The activation of the GIP, GLP-1, and GCG receptors simultaneously by retatrutide leads to better weight reduction and cardiometabolic benefits compared to targeting a single receptor
We generally advise against it if you have any of the following: History of Medullary Thyroid Cancer: The drug is a GLP-1 receptor agonist, which has been shown to cause recurrences of thyroid tumors in patients with a history of it
Maximum dose: 2.4 mg weekly
International Bipolar Foundation
Semaglutide demonstrates benefits for reducing the risk of major undesired cardio and vascular events in people with type 2 diabetes