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While GLP-1RAs demonstrate immunomodulatory potential relevant to SS pathogenesis through their effects on key immune cell populations, direct experimental evidence characterizing their impact on SS-specific immune dysregulation remains strikingly limited

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Plant Cell 10:753764 Noctor G, Mhamdi A, Foyer CH (2016) Oxidative stress and antioxidative systems: recipes for successful data collection and interpretation

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However, semaglutide also produces less weight loss than retatrutide, so the higher GI burden comes with proportionally greater efficacy