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Role of bacterial translocation in necrotizing enterocolitis

Oksanen J, Blanchet FG, Kindt R, Legendre P, Minchin PR, O'Hara RB, Simpson GL, Solymos P, Stevens MHH, Wagner H

Adv Exp Med Biol (2015) 803:2939

Background and aims: Sedentary ageing accelerates decline of metabolic health and cognitive reserve, while regular exercise effectively supports metabolic and cognitive health in ageing population

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We discuss how each of these leads to ASD to better understand the mechanisms, with the goal of mitigating risk and developing potential therapeutics (Figure 1)