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Nicotine and added sugar, two prime ingredients, can cause major depression, anxiety, dysthymia, and bipolar disorder

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Contrary to PHEs findings the US Centers for Disease Control and Prevention (CDC) a federal agency dedicated to safeguarding health does not endorse vaping as an alternative to smoking or as an effective tool for quitting

Juul's founders applied for a patent in 2014 that described methods for alerting the user or disabling the device when the dose of a drug such as nicotine exceeds a certain threshold

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These findings suggested that the gut microbiome was particularly sensitive to early-life THS exposure, highlighting the long-term impact of environmental tobacco toxins on microbial diversity [101]