For diabetes treatment, NICE recommends continuing GLP-1 therapy only if HbA1c has fallen by at least 11 mmol/mol (1%) and weight has reduced by at least 3% after approximately 6 months, unless there are individual clinical reasons to continue
The Role of Lifestyle Modifications Effective weight loss with GLP-1 medication often relies on the incorporation of lifestyle modifications
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Intermittent, high-dose iron supplementation (i.e., one, two, or three times a week on non-consecutive days) may be a feasible alternative to daily iron supplementation among pregnant women who are at low risk of developing anemia and have adequate antenatal care (182)
For patients and families navigating mental illness, online communities can serve as a lifeline, particularly where mental illness carries high stigma or goes unrecognized
Cory Mellon, MD Last reviewed May 2026