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These effects include body weight loss and reduced hepatic lipid accumulation, which are important cornerstones in the treatment of obesity and NAFLD

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IGF-1 LR3 is a modified analog of human Insulin-Like Growth Factor-1, engineered with two structural changes an arginine substitution and a 13-amino acid N-terminal extension that reduce its binding to IGF-1 binding proteins

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doi: 10.1016/j.semarthrit.2021.11.013 8 Souto-CarneiroMTthLBehnischRUrbachKKlikaKDCarvalhoRAet al