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These features were consistent with those observed in chronically exposed bronchial epithelial cells, indicating that oxidative adaptation can also occur at the tissue level

Among non-nicotine controls, cigarette smoking abstinence ranged from 3.9% self-reported continuous abstinence (66) to 46% abstinence (measure not reported) (64)

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Neural circuits and nicotinic acetylcholine receptors mediate the cholinergic regulation of midbrain dopaminergic neurons and nicotine dependence