These are the kinds of details that never appear in the clinical literature but make a real difference in daily practice
Combination with Insulin with or without Metformin In a 26-week double blind trial (Trial 6, NCT03021187), 731 adult patients with type 2 diabetes mellitus inadequately controlled on insulin (basal, basal/bolus or premixed) with or without metformin, were randomized to semaglutide tablets 3 mg, 7 mg and 14 mg orally once daily or placebo once daily
The answer is not a simple yes or no, as it depends on whether the vial has been opened and the specific guidelines provided by the pharmacy
It provides enough semaglutide to last through the initial titration phases, reduces the per-milligram cost compared to smaller vials, and does not require the commitment of a 15 mg vial that might expire before you use it all
Some researchers prefer 27 gauge for drawing from bacteriostatic water vials and 29-31 gauge for the semaglutide vial itself
and STEP 3 Investigators (2021)