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Rag 2 -/- mice, as previously described (53) and white C57BL/6 were crossed to C57BL/6.Rag for the generation of white C57BL/6.Rag2 -/- mice for at least 5 generations

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SIRT1 and oxidative stress Brain tissue has superior oxygen metabolism with low antioxidant capacity resulting in oxidative stress which damages DNs in the SN (Parga et al

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Lepore JJ, Olson E, Demopoulos L et al (2016) Effects of the Novel Long-Acting GLP-1 Agonist, Albiglutide, on cardiac function, cardiac metabolism, and exercise capacity in patients with chronic heart failure and reduced ejection fraction